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Updated: Sep 10, 2025

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
09:29

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy

Published on: May 4, 2016

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CDK5はシンフィリン-1ユビキチン化と基礎ミトファギーを阻害する:パーキンソン病への影響

Mor Savyon1, Eyal Avraham1, Ankit Kumar Shah1

  • 1Department of Biochemistry, The B. Rappaport Faculty of Medicine and Institute of Medical Research, Technion-Israel Institute of Technology, Haifa 31096, Israel.

International journal of molecular sciences
|August 28, 2025
PubMed
まとめ

パーキンソン病 (PD) は 神経細胞の喪失を伴う. この研究では,CDK5がシンフィリン-1をリン酸化し,その保護機能を低下させ,PDの病原化に潜在的に寄与していることが示されています.

キーワード:
CDK5 についてパーキンソン病ミトファジー神経変性ニューロンのプロセスシンフィリン-1ユビキチネーション

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Author Spotlight: Fluorescence-Based Quantification of Mitochondrial Membrane Potential and Superoxide Levels Using Live Imaging in HeLa Cells06:57

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