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Updated: Sep 10, 2025

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

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BRD4 媒介子 成長因子β誘発的平滑筋細胞のメゼンキマ原始細胞からの微分化

Ayobami Olajuyin1, Venkatakirankumar Mandlem1, Christudas Sunil1

  • 1Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA.

International journal of molecular sciences
|August 28, 2025
PubMed
まとめ

ブロモドメインを含むタンパク質4 (BRD4) は,滑らかな筋肉細胞 (SMC) の微分化の新しい調節剤である. 血管の発達に不可欠なTAZとミオカルディンを調節することによってSMCマーカーの発現を制御します.

キーワード:
BRD4 についてTAZ についてTGF-β区分するミオカルディン滑らかな筋肉細胞

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TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing07:05

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