頭頸部がん患者における口頭痛と頭痛の臨床的特徴とメカニズムの概要
Ernesto Anarte-Lazo1, Carlos Bernal-Utrera2
1Faculty of Health, UNIE University, 28015 Madrid, Spain.
Journal of clinical medicine
|August 28, 2025
まとめ
頭頸部がん患者では 顔面の痛みや頭痛が一般的ですが 解明は不十分です これらの障害症状の診断と治療に 標準化された評価が必要です
科学分野:
- 腫瘍学
- 痛みの治療
- 神経学
背景:
- 頭と首の癌 (HNC) の患者では,耳と顔の痛み (OFP) と頭痛が頻繁に見られる.
- 臨床的特徴と痛みのメカニズムは十分に研究されていないため,診断と管理に影響を与えています.
- このレビューは,OFPとHNC患者の頭痛に関する現在の文献をまとめています.
研究 の 目的:
- 頭頸部がん患者における口頭痛と頭痛の臨床的特徴をレビューする.
- 痛みの特徴と潜在的メカニズムを説明する.
- これらの状態に使用される評価ツールを特定します.
主な方法:
- 確立されたガイドライン (ArkseyとO'Malley, PRISMA-ScR) に従って,スコーピングレビューが行われました.
- 主要な科学データベース (PubMed,Embase,Scopus,Web of Science) で検索が行われました.
- 定量的な研究も定性的な研究も含み,データを記述的に合成した.
主要な成果:
- 32件の研究が含まれており,そのほとんどは観察的であり異質的であった.
- Orofacialの痛みは,しばしば神経疾患 (13. 1% - 64. 5%) で,しばしば腫瘍部位に位置する.
- 疼痛は生活の質に大きく影響し,中心的な感受性が示唆されているが,機械的分類は限られている.
結論:
- 顔の痛みと頭痛は頭頸部がんでは一般的です
- 標準化された検証ツールが不可欠です
- ターゲットを絞った治療戦略の開発には,フェノタイプ化の改善が不可欠です.
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