関連する実験動画

Updated: Sep 10, 2025

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
06:48

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells

Published on: June 16, 2022

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イントロン保持:RNA生物学と転写後の遺伝子調節における再出現パラダイム

Ana L Porras-Tobias1, Abigail Caldera1, Isabel Castro-Piedras1

  • 1Center for Biotechnology and Genomics, Texas Tech University, Lubbock, TX 79409, USA.

Genes
|August 28, 2025
PubMed
まとめ

かつてスプライシングノイズと考えられていたイントロン保持 (IR) は,現在,遺伝子発現,mRNAの運命,およびタンパク質の多様性に影響を与える重要な規制メカニズムとして理解されています. IRの調節不良は 癌や神経変性などの病気と関連しています

キーワード:
AS についてIR についてIR 規制の乱れNMD老化する代替スプライシング癌についてイントロン保持神経変性無意味な媒介による衰退

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In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
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