予測性微生物マーカーは,アダリムマブへの反応と反応しない人を区別する: 潰瘍性大腸炎における精密医療への一歩

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Updated: Sep 9, 2025

Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing
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Shaghayegh Baradaran Ghavami1, Arfa Moshiri2, Carola Bonaretti3

  • 1IBD Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran.

Microorganisms
|August 28, 2025
PubMed
まとめ

潰瘍性大腸炎 (UC) に対するアダリムマブ治療は,腸内微生物を糞便と大腸組織で異なった形で変化させる. 回答者は便の微生物群の改善を示していますが,大腸の組織は不活性であり,ニッチ特有の微生物群分析の必要性を強調しています.

キーワード:
メイオスコアTNFα阻害剤による治療粘膜メタゲノミクス便のメタゲノミクス潰瘍性大腸炎

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