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抗ウイルス薬におけるPROTAC:現在の進歩と将来の見通し

Jiacheng Jin1, Mengxiang Quan1, Xueyan Cao1

  • 1Affiliated Yongkang First People's Hospital and School of Pharmacy, Hangzhou Medical College, Hangzhou 310013, China.

Molecules (Basel, Switzerland)
|August 28, 2025
PubMed
まとめ

Proteolysis-targeting chimera (PROTAC) 技術は,ウイルスタンパク質を分解することで抗ウイルス治療の新たなアプローチを提供します. この方法は,SARS-CoV-2やHBVのようなウイルスに対して有望であり,薬剤耐性やウイルスの変異に対処します.

キーワード:
プロタック抗ウイルス療法薬剤耐性ホスト 病原体との相互作用標的型タンパク質の分解

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