関連する実験動画
Updated: Sep 9, 2025
10:10
Reverse Total Shoulder Arthroplasty
Published on: July 5, 2011
43.4K
肩や肘の整形手術を受けた患者のビタミンD欠乏症の高い発生率
Miledi Hoxha1, Tizian Heinz2, Maximilian Rudert1,2
1Orthopaedic Center for Musculoskeletal Research, University of Wuerzburg, 97074 Wuerzburg, Germany.
Nutrients
|August 28, 2025
まとめ
ビタミンD欠乏症は,上肢の関節置換手術を受けた患者で一般的です. 補給は欠乏症のリスクを大幅に減らすため,手術前のビタミンD検査が推奨されます.
科学分野:
- 整形外科
- 内分泌学
- 栄養学
背景:
- ビタミンD欠乏症は 世界中で約10億人に及ぶ 世界的な健康問題です
- 低ビタミンDレベルは,特に全関節整形手術 (TJA) を受けている患者の整形外科状態と手術結果に悪影響を及ぼします.
- 上肢 (肩と肘) の関節整形手術を受けた患者のビタミンD状態に関する研究は限られている.
研究 の 目的:
- 肩関節整形手術や肘関節整形手術を予定している患者のビタミンD欠乏症の有病率を決定する.
- この患者集団における低ビタミンDの潜在的な危険因子を特定する.
主な方法:
- 全肩または肘の関節整形手術を受けた108人の患者で,手術前の血清25- ヒドロキシビタミンD (25OHD) レベルを測定した.
- リスク要因を特定するために,人口統計データ,手術後の情報,および併発症が収集されました.
- ビタミンD欠乏症の危険因子を特定するために,多変量回帰分析を用いた.
主要な成果:
- 定期的なビタミンD摂取を報告しなかった患者の多くは (87%) 血清ビタミンD濃度が低く,63. 6%が欠乏していた.
- ビタミンDサプリメントを摂取した患者は,サプリメントを摂取しなかった患者よりビタミンD濃度が有意に高かった (平均36. 4ng/ ml対18. 4ng/ ml).
- ビタミンDの濃度は季節的に変化し,春には最も低く,夏には最も高い.
結論:
- 肩や肘の関節整形手術を受けた患者は,ビタミンD低下のリスクが高い.
- ビタミンDサプリメントは,欠乏症の確率を 94% 減少させました.
- 季節的要因は低ビタミンDレベルの主な危険因子であり,手術前のビタミンDレベル測定は標準的なケアであるべきだと示唆しています.
関連する概念動画
01:22Connective Tissue Cell Types
3.4K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.4K
01:23Role of Skin in Vitamin D Synthesis
5.6K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.6K
01:25Role of Vitamins in Maintaining Bone Health
3.6K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.6K