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Updated: Sep 9, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
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メラノーマにおける治療介入に対する抵抗性の形成における腫瘍の微小環境ダイナミクス:ナラティブレビュー

Laci M Turner1, Hanna Terhaar1, Victoria Jiminez1

  • 1Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

Pharmaceuticals (Basel, Switzerland)
|August 28, 2025
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) に対するメラノマ耐性には,複雑な腫瘍微環境 (TME) の変化と免疫回避が含まれます. これらのメカニズムを理解することは 耐性腫瘍の 個別化された治療法の開発の鍵です

キーワード:
CTLA-4 についてPD-L1 について免疫チェックポイント阻害剤メラノーマレジスタンス腫瘍の微小環境

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