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Updated: Sep 9, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

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イノベーションから合併症へ:ICIによって引き起こされる免疫関連大腸炎に関する症例報告とレビュー

Huibo Li1,2, Yumiao Pan1,3, Wenzheng Liu4

  • 1Department of Pharmacy, Peking University Third Hospital, Beijing 100191, China.

Pharmaceuticals (Basel, Switzerland)
|August 28, 2025
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) は,重度の免疫関連大腸炎 (ir- colitis) を引き起こす可能性があります. ICIの副作用の有効な治療には,早期発見と多分野的な治療,コルチコステロイドを含むことが不可欠です.

キーワード:
大腸炎腹免疫チェックポイント阻害剤免疫関連の有害事象シンチルマブ

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Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells06:57

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