4-ヒドロキシカルコンは,EGFR/AKT/ERK1/2シグナル伝達経路をターゲットにすることで,ヒトコロナウイルスHCoV-OC43を抑制する

Yuanyuan Huang1,2, Jieyu Li1,2, Qiting Luo2

  • 1School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.

Viruses
|August 28, 2025
PubMed
まとめ

4-ヒドロキシカルコン (4HCH) は,ヒトの新型コロナウイルスHCoV-OC43に対する強力な抗ウイルス効果を示しています. この化合物は,表皮成長因子受容体 (EGFR) 経路を標的にしてウイルスの複製を阻害し,新型コロナウイルス治療の可能性がある.

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