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Updated: Sep 9, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

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Published on: March 2, 2014

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ウイルスのタンパク質によるプライマリシーケンスの固有免疫回避は,CTLベースのワクチン戦略を導く

Li Wan1,2, Masahiro Shuda1,2, Yuan Chang1,2

  • 1Cancer Virology Program, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Viruses
|August 28, 2025
PubMed
まとめ

ウイルスは,タンパク質合成を遅らせて細胞毒性Tリンパ球 (CTLs) を回避するために,固有のゲノムでコードされた要素を使用します. この免疫回避戦略は,プライマリシーケンスの内在免疫回避 (PSI) と呼ばれ,潜伏期間にウイルスが検出されないままにします.

キーワード:
CTLベースのワクチンMHC Iプライマリシーケンスの内在免疫回避

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