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Updated: Sep 9, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on: January 7, 2019

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Orfウイルスベースのベクトルは,強力な生殖中心のB細胞,Tfh細胞およびCD8+T細胞応答を誘発する

Anna Lena Kastner1, Melanie Müller2, Anna-Friederike Marx1

  • 1Department of Biomedicine, Division of Experimental Virology, University of Basel, 4009 Basel, Switzerland.

Molecular therapy : the journal of the American Society of Gene Therapy
|August 28, 2025
PubMed
まとめ

再結合オルフウイルス (rORFV) ワクチンは,B細胞とT細胞を効果的に刺激し,保護性免疫記憶を生成します. ブースター接種はこれらの反応を強化し,rORFVを多用途のワクチンベクターとして強調します.

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