羊における後腸酸性誘発による,小腸の発酵と腸の浸透性への影響

Haley F Linder¹, Emma G Prybylski¹, Brett R Loman¹

¹Department of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, IL, USA, 61801.

Journal of animal science

|August 28, 2025

まとめ

羊の後腸酸性誘発は,腸と腸のpHを低下させ,発酵に影響を及ぼした. 腸の浸透性は様々な反応を示したが, rumenの状態に対する全身的な効果が観察された.

科学分野:

動物科学
類の栄養
胃腸内科

背景:

後腸酸性症は,反性の動物における消化機能を乱す可能性があります.
発酵と腸壁の整合性への影響を理解することは動物の健康にとって極めて重要です

研究の目的:

羊の誘発性後腸酸性症 (HGA) の影響を調査する.
腸内pHの変化, ruminal発酵, 腸内浸透性を評価する.

主な方法:

綿羊は,小麦粉の継続的なセカル注入を含むコントロール (CON) またはHGA治療を受けた.
,,糞便のサンプルをpHと揮発性脂肪酸 (VFA) について分析した.
クロミウムEDTA,スクラロース,およびex vivoUssing室技術を用いて腸の浸透性を評価した.

主要な成果:

HGAは,セカルとのpHを大幅に低下させ,また, rumenのpHを低下させました.
糞便のVFA濃度はHGAの雌羊で増加し,反性のVFAとアンモニアの濃度は減少した.
HGAの雌羊のCecal組織は,透過性の増加 (TEERの減少) の傾向を示したが,イレアルおよび大腸の透過性は影響を受けなかった.

結論:

羊の粉の注入は後腸酸化を効果的に誘発した.
後腸酸性症は後腸発酵に影響し,腸のパラメータに全身的な影響を及ぼします.
腸の浸透性反応は局所的であり,腸の浸透性が増加する傾向がありました.

キーワード:

後腸酸性症漏れする腸

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