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Updated: Sep 9, 2025

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

Published on: October 25, 2024

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甲状腺ホルモン受容体β (TR-β) 信号は,自己免疫疾患における病原性Th17細胞を制御する

Yoshimitsu Doi1,2, Ben J E Raveney1, Atsuko Kimura1

  • 1Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8502, Japan.

International immunology
|August 28, 2025
PubMed
まとめ

甲状腺ホルモン受容体β (TR-β) は,病原性Tヘルパー17 (Th17) 細胞の分化とIL-17の産生を独占的に誘導し,自己免疫疾患の重度に影響を与える. TR-βシグナリングは,免疫反応に不可欠なIL-10/IL-17バランスに影響します.

キーワード:
新しい脂質生成IL-10 についてIL-17 についてIL-1βソベティローム

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