主要な胞性リンパ球性ホジキンリンパ腫 (NLPHL):幼い子供の最初の報告症例
Josselyn Sofia Vergara1, Lianna Jean Marks2, Oscar Silva1
1Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
まとめ
胞性リンパ球が優勢であるホジキンリンパ腫 (NLPHL) は,まれに,主に小児の臓に現れます. この症例報告では, 脊髄外除術から3年後に 治療を受けることなく 疾患のない状態に達した 脊髄性NLPHLの患児の詳細が示されています.
科学分野:
- 血液学
- 小児腫瘍学
- 病理学について
背景:
- 結節性リンパ球優勢のホジキンリンパ腫 (NLPHL) は珍しいB細胞リンパ腫で,通常は鈍化し,リンパ節に影響します.
- NLPHLにおける臓の関与は,しばしば進行した病気と悪い予後を示します.
- 主要な臓NLPHLは,特にノダルの関与のない小児の症例では,非常にまれです.
研究 の 目的:
- 小型の胞性リンパ球が優勢である子供のホジキンリンパ腫の最初の症例を報告する.
- 脊髄切除術後の小児原発性脊髄NLPHLにおける好ましい結果の可能性を強調する.
主な方法:
- NLPHLと診断された小児患者の症例報告
- 臨床表現,診断結果,治療 (切除術),およびフォローアップのレビュー
- 脊髄組織におけるNLPHLの病理的確認
主要な成果:
- 患者さんは,明らかに結節疾患がない,孤立した関節関節関節関節関節関節関節関節関節関節関節関節関節関節
- 脊髄切除術後,3年間の追跡調査で,追加の治療を必要とせず,子どもは病気から自由のままです.
- この結果は,NLPHLにおける臓関わりに関連した,一般的により悪い予後とは対照的です.
結論:
- 幼児における原発的な臓NLPHLは 稀ですが 予後は良好です
- 脊髄切除術だけでは小児原発性NLPHLの治療には十分である.
- このケースは,小児の集団におけるNLPHLのプレゼンテーションと管理の理解を広げています.
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