関連する実験動画

Updated: Sep 9, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
11:06

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

Published on: January 31, 2022

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"次世代の"GLP-1Rダヌグリプロンおよびロティグリプロン類アゴニスト:特許レビュー (2020-2024)

Elena V Tolkacheva1, Alexandr Yu Saliev1, Tagir L Salakhov1

  • 1Medicinal Biotechnology Department, Sirius University of Science and Technology, Olimpiyskiy ave. 1, Sirius, Krasnodar Region, 354340, Russia.

Current medicinal chemistry
|August 28, 2025
PubMed
まとめ

次世代の口服用グルカゴン型ペプチド-1 (GLP-1) 受容体アゴニストは,2型糖尿病と肥満の治療に有望である. 構造的改変は,強力な小分子GLP-1Rアゴニストの開発の主要な傾向を示しています.

キーワード:
2型糖尿病ダヌグリプロングルカゴン類ペプチド-1受容体アゴニストロティグリプロン次のクラスの薬物非ペプチドール経口アゴニスト小分子アゴニスト構造と活動の関係

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