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Updated: Jul 31, 2026

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
11:28

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus

Published on: October 7, 2011

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[ヘルペスシンプレックスウイルス2型エンベロープグリコタンパク質gDを発現する新しいmRNAワクチンの開発と免疫性評価]

Jialuo Bing1, Liye Jin1, Yao Deng2

  • 1School of Public Health, Xinxiang Medical University, Xinxiang 453003, Henan, China.

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|August 28, 2025
PubMed
まとめ

新種のリポポリプレックスによるmRNAワクチン (gD-ORI mRNA) は,生殖器ヘルペス予防に有望であることが示されています. このヒトアルファヘルペスウイルス2 (HSV-2) に対するワクチンは,マウスの強烈で長期にわたる抗体およびT細胞反応を誘発した.

キーワード:
封筒のグリコタンパク質 gDヘルペス・シンプレックスウイルス2型免疫反応リポポリプレックスmRNAワクチン

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Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...