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Updated: Sep 9, 2025

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
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[人工的に強化されたプロモーターTCIN5Bの構築と最適化]

Meng Guo1, Shuxin Dong1, Jun Li1

  • 1Key Laboratory of Medicinal Molecule Science and Pharmaceutical Engineering, Ministry of Industry and Information Technology, Institute of Biochemical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China.

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|August 28, 2025
PubMed
まとめ

研究者は酵母細胞工場のための 新規のストレス反応性プロモーターを開発しました この戦略は,高温ストレス条件下での天然化合物の生産を強化します.

キーワード:
サッカロミセス・セレヴィセアプロモーターエンジニアリングストレス反応転写因子 CIN5

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The eukaryotic promoter region is a segment of DNA located upstream of a gene. It contains an RNA polymerase binding site, a transcription start site, and several cis-regulatory sequences.  The proximal promoter region is located in the vicinity of the gene and has cis-regulatory sequences and the core promoter. The core promoter is the binding site for RNA polymerase and is usually located between -35 and +35 nucleotides from the transcription start site. The distal promoter regions are...
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