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Updated: Sep 9, 2025

The Soft Agar Colony Formation Assay
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KCTD10は,ユビキチン媒介のβ-カテニンの分解によって肺がんの転移と血管新生を抑制する

Zihao Yin1,2, Shengwen Long1,2, Hao Zhou1,2

  • 1The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Science, Hunan Normal University, Changsha, China.

Frontiers in immunology
|August 28, 2025
PubMed
まとめ

KCTD10は,β-キャテニンを分解し,PD- L1発現を減少させ,肺がんを抑制する. 肺がんの進行と転移に対して,抗PD-1療法と併用したKCTD10の過剰発現は,相乗効果を示している.

キーワード:
KCTD10 についてM6A についてPD-1 について肺がんの転移特定のKctd10 ノックアウトβ-カタニン

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