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Updated: Sep 9, 2025

Generation of Human Chimeric Antigen Receptor Regulatory T Cells
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自体免疫疾患におけるCAR T細胞療法:前向きな前線

Dehong Wu1,2, Zijun Y Xu-Monette1, Jia Zhou3

  • 1Division of Hematopathology, Department of Pathology, Duke University Medical Center, Durham, NC, United States.

Frontiers in immunology
|August 28, 2025
PubMed
まとめ

化学抗原受容体 (CAR) T細胞療法では,有害なB細胞を標的にすることで,自己免疫疾患の治療に有望であることが示されています. 潜在的な治療に対する安全性と長期的な有効性を確認するには,さらなる試験が必要です.

キーワード:
CAR T細胞療法トレグ細胞自己免疫疾患自己反応性B細胞をターゲットにするパーソナライズされたリスクの分層

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