関連する実験動画

Updated: Apr 12, 2026

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
13:26

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry

Published on: September 13, 2014

61.9K

潜在的ヘクソキナーゼ2阻害体としての天然化合物の計算評価

Abdullahi Ibrahim Uba1, Eleonora Procino2, Lorenza Marinaccio2

  • 1Department of Molecular Biology and Genetics, Istanbul AREL University, 34537 Istanbul, Turkey.

In silico pharmacology
|August 28, 2025
PubMed
まとめ

ハイパーソイドのような天然のフェノリックは,がん代謝に重要な酵素であるヘクソキナーゼ2 (HK2) の阻害剤として有望である. この研究では,HK2抑制のための100の天然製品を計算的にスクリーニングすることによって,潜在的な天然の抗がん化合物を特定しました.

キーワード:
癌の代謝グライコリチス酵素の抑制シリコン分析リード最適化自然製品による薬物発見フェノール化合物タンパク質とリガンドの相互作用仮想スクリーニング

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