術後の栄養状態と,口腔外科手術後の唾液のバクテリア負荷の関係
Teruyuki Niimi1, Sakiko Soutome2, Akira Imakiire2
1Division of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.
Cureus
|August 28, 2025
まとめ
整体抗生物質は,口腔手術後の唾液細菌を効果的に減少させます. しかし,経口摂取量を減らすと細菌数が増加し,手術部位感染 (SSI) を防ぐために食事の移行時に口腔衛生の強化の必要性を強調します.
科学分野:
- 口腔・口腔外科
- 微生物学
- 感染症
背景:
- 口腔外科手術は,唾液細菌による手術部位感染 (SSI) に易感な,汚染された傷を生み出します.
- 手術後の栄養状態が唾液のバクテリア負荷に与える影響は十分に理解されていません.
研究 の 目的:
- 術後の栄養状態と唾液中の細菌数との関係を調べる.
- 異なる食事段階における唾液細菌レベルに対する全身性抗生物質の影響を評価する.
主な方法:
- 24人の患者 (≥6年) を対象とした前向きな観察研究では,手術後の腸内栄養による口腔手術が行われました.
- 16S rRNA遺伝子のリアルタイムPCRを用いて,手術前および液体,腸内,通常のダイエットフェーズで測定された唾液細菌数.
- 統計分析に使用されるペア型tテスト.
主要な成果:
- 腸内投与中の全身抗生物質は,手術前の唾液細菌レベル (101%) を維持した.
- 細菌の数は抗生物質の投与で減少 (88%) したが,その投与なしでは増加 (122%) した.
- 通常のダイエット段階では,数値がベースライン (98%) に戻った.
結論:
- 経口手術後の唾液細菌の増殖を抑制するために,全身の抗生物質は不可欠です.
- 特に食事の移行時に,経口摂取量を減らすと,細菌の負荷が増加する可能性があります.
- SSIのリスクを軽減するために,追加の口腔衛生対策を実施することが推奨されます.
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