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Updated: Sep 9, 2025

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
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ゲノム幅のプレオトロピー分析により,冠動脈疾患と癌に影響を与える共有および反対の経路が特定される

James Yarmolinsky1, Evelyn Lau2, Fotios Koskeridis1

  • 1Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom. (J.Y., F.K., M.J.G., A.D., I.T.).

Arteriosclerosis, thrombosis, and vascular biology
|August 28, 2025
PubMed
まとめ

この研究では,冠動脈疾患 (CAD) とがんの共通の遺伝因子を明らかにし,新しい位置と二重予防のための潜在的な薬標的を特定しました. 発見はまた,両疾患の遺伝的効果と薬物効果の相反を強調しています.

キーワード:
血圧心血管疾患併発症冠動脈疾患リスク要因

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