炎症性腸疾患における妊娠の管理に関するグローバルコンセンサス声明
Uma Mahadevan1, Cynthia H Seow2, Edward L Barnes3
1Division of Gastroenterology, Department of Medicine, University of California, San Francisco, California, USA.
Alimentary pharmacology & therapeutics
|August 28, 2025
まとめ
この研究は,妊娠中の炎症性腸疾患 (IBD) の管理に関する世界的なコンセンサスを提供し,母と乳児の健康状態を改善するためのデータ主導のガイドラインを提供します.
科学分野:
- 胃腸内科
- 産婦人科
- 公衆衛生
背景:
- 炎症性腸疾患 (IBD) の女性の妊娠は,治療と管理に関する高品質のデータが限られているため,ユニークな課題を提示します.
- 患者や医療従事者の知識不足が 妊娠率や薬の服用率や健康上の結果に 影響を及ぼしています
- 矛盾する国際的ガイドラインは 標準化された証拠に基づいた勧告の必要性を強調しています
研究 の 目的:
- 妊婦の炎症性腸疾患 (IBD) の管理のためのベストプラクティスに関する世界的なコンセンサスを確立する.
- 妊娠中のIBD患者に対する知識のギャップを埋め,ケアを標準化する.
- 母親と乳児の健康状態を改善するためのデータ主導のガイドラインを策定する.
主な方法:
- GRADE (Grading of Recommendations Assessment, Development, and Evaluation) プロセスを利用し,データに基づいた推奨を行いました.
- RANDプロセスは,公表されたデータが不十分である専門家のコンセンサスを必要とする分野に使用されました.
- 幼児の健康を支えるための礎石として母親の健康を優先する.
主要な成果:
- 10つの主要なトピックカテゴリーで34のGRADE勧告と35のコンセンサス声明を開発しました.
- 現在のデータと専門家の意見を統合し,包括的な指針を策定しました.
- 証拠に基づいた実践を強化するためにさらなる研究を必要とする分野を特定しました.
結論:
- グローバル・コンセンサス・コンソーシアム (Global Consensus Consortium) は,妊娠中のIBDのグローバルな管理のための実用的でデータに基づいたガイドラインを提供しています.
- IBDを患っている妊婦と乳児のケアの一貫性を向上させることを目的としています.
- 専門家の国際的協力と 患者支援の重要性を強調し 臨床的実践を洗練する
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