化学療法実践の最適化: 投与量帯の再発行と廃棄物の削減への影響
Alida Geertruida Catharina van Huët1,2, Helle-Brit Fiebrich-Westra3, Peder Nygård1
1Department of Pharmacy, Isala Hospital, Zwolle, Netherlands.
まとめ
パクリタキセルやオクサリプラチンなどの化学療法剤の用量帯は,添加物の再発行を増加させ,薬物の廃棄を大幅に減少させた. このイニシアチブにより,医療の持続性とコスト効率が向上し,年間約5200ユーロが節約されました.
科学分野:
- 腫瘍学
- 医薬品科学
- 医療管理
背景:
- 精密な用量要件により,化学療法製剤はしばしば無駄になります.
- 再構成された化学療法剤の互換性は限られており,持続可能性に影響します.
- 投与量帯は,浪費を軽減し,がん治療のコスト効率を改善することを目的としています.
研究 の 目的:
- 化学療法添加物の再配給に対する用量帯の影響を評価する.
- 薬の浪費を減らすための用量帯の効果を評価する.
- 投与量帯の実施による経済的利益を定量化する.
主な方法:
- Hix 6. 2では,最大10%の偏差を持つ用量帯が実装されました.
- 薬物の廃棄物と添加物の再発行は,導入前と後に比較された.
- 経済的利益は,製品,材料,製造コストに基づいて計算されました.
主要な成果:
- ほとんどの薬剤,特にオキシリプラチン (3. 7% から 27. 8%) の化学療法添加物の再発行が増加した.
- パクリタキセルを含む薬剤の廃棄量は有意に減少しました (90から23の添加物).
- 年間約5200ユーロのコスト削減を達成しました.
結論:
- 投与量帯は化学療法剤の互換性を高め,再発行を増加させる.
- この手順は,化学療法の準備における薬物の浪費を効果的に削減します.
- 投与量帯のより広範な実施は,化学療法サービスをさらに最適化することができます.
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