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Updated: Sep 9, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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既定のがん傾向遺伝子は,単一および複数がんの診断において

Jeffrey W Shevach1, Jianfeng Xu2, Nathan Snyder1

  • 1Department of Medicine and the Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina.

JAMA oncology
|August 28, 2025
PubMed
まとめ

16のがん誘発性遺伝子の稀な病原性変異 (RPV) は,大規模な集団研究において,単発性および多発性がんの診断の確率の増加と関連している. 多遺伝子パネルテストは,これらの変異を持つ個人に有益である可能性があります.

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