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Updated: Sep 9, 2025

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結界粘着分子Cは,内皮界面におけるインテグリン粘着を調節することによって,膠芽細胞のような幹細胞の侵入を制限する

Sara Rosińska1, Gwennan André-Grégoire2, Mathilde Kerhervé1

  • 1CRIC2NA, CNRS, Inserm, Nantes Université, University Angers, 44000 Nantes, France; Équipe Labellisée Ligue contre le Cancer, 75013 Paris, France.

Cell reports
|August 28, 2025
PubMed
まとめ

結合粘着分子C (JAMC) は,血管に細胞の広がりを制限することによって,膠芽細胞のような幹細胞 (GSC) の侵入を抑制します. JAMCの損失は,GSCの侵入性を悪化させ,JAMCを強調する生存率を低下させます.

キーワード:
CP: がんについてGBMJAMC粘着する内皮細胞グリオブラストーマ侵入するメゼンキマール周縁のニッチ

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