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Updated: Sep 9, 2025

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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NAB2-STAT6は単一繊維性腫瘍におけるEGR1依存神経内分泌プログラムを駆動する

Connor Hill1,2, Alexandra Indeglia1,3, Francis Picone1

  • 1The Wistar Institute, Philadelphia, United States.

eLife
|August 28, 2025
PubMed
まとめ

単離性繊維性腫瘍 (SFT) は,遺伝子発現を変化させることで腫瘍の成長を促すNAB2-STAT6遺伝子の融合を伴う. この発見は悪性SFTの新たな治療目標を示しています

キーワード:
がん生物学遺伝子についてゲノム学人間神経内分泌珍しい腫瘍転写因子

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