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Updated: Sep 9, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

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異なる相互作用モードは,ASC PYDとCARDドメインのポリメリゼーションをフィラメント状の構造にオーケストラします

Hasan Ozan Otas1, Nesrin Erkol1,2

  • 1Apoptosis and Cancer Immunology Laboratory, Department of Molecular Biology and Genetics, Bogazici University, Istanbul, Turkey.

The FEBS journal
|August 28, 2025
PubMed
まとめ

CARD (ASC) アダプタータンパク質を含むアポトーシスに関連した斑状のタンパク質は,先天的な免疫を調節し,腫瘍抑制剤として作用する. この研究は,炎症体組成と機能に不可欠なASCドメインポリメリゼーションの協力的メカニズムを明らかにしています.

キーワード:
ASC についてカードFRET についてPYDオリゴメリゼーション

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