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Updated: Sep 9, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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カリバンはDNA損傷に対するp53の転写標的である

Jiaqian Cui1, Haiyan Zhang1, Yan Cheng2

  • 1Medical School of Nantong University, Nantong, China.

PloS one
|August 28, 2025
PubMed
まとめ

DNA損傷はp53を活性化させ アポトーシスの重要なレギュレータであるCalibanの発現を直接増加させます この研究は,p53の直接的な転写標的としてCalibanを特定し,DNA損傷応答におけるその役割を明確にしています.

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