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Updated: Sep 9, 2025

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
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ARRDC4媒介の糖解は,フルークトーゼ-1,6-ビスホスファートを通じて,インフルエンザAウイルスに対する先天的な免疫を強化する

Yuhan Li1,2,3,4, Zhen Wang1,2,3, Jie Wang1,2,3

  • 1State Key Laboratory of Veterinary Public Health and Safety, Department of Preventive Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.

Proceedings of the National Academy of Sciences of the United States of America
|August 28, 2025
PubMed
まとめ

アレスティンドメイン4 (ARRDC4) は,A型インフルエンザウイルス (IAV) 感染を感知し,グルコース代謝酵素,筋肉型 (PFKM) およびその産物であるフルークトーゼ-1, 6 ビスファート (FBP) を介して抗ウイルス免疫を強化します. この経路はウイルスの感染に対する 生まれつきの免疫反応を強化します

キーワード:
ARRDC4 についてフルクトーゼ-1,6-ビスホスファートインフルエンザ生まれつきの免疫ウイルスの複製

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