関連する実験動画

Updated: Sep 9, 2025

Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source
06:37

Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source

Published on: February 7, 2013

16.8K

Corynebacterium diphtheriaeにおけるCHTおよびHtaA血球によるヘムスキャビングの構造的基礎

Jordan Ford1, Andrew K Goring1, Yuri Lee1

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, CA 90095, USA.

The Journal of biological chemistry
|August 28, 2025
PubMed
まとめ

Corynebacterium diphtheriaeは,ChtAおよびHtaAタンパク質の保存領域 (CR) を使用して,鉄分豊富なヘムを取り除きます. 構造と結合の研究は,これらのドメインがヘモグロビンからヘムを捕獲し,細菌の鉄の吸収を助ける方法を示しています.

キーワード:
バクテリアの病原性保護地域ドメインコリネバクテリア・ディフテリアX線結晶学電子パラマグネティック共振ヘムヘモフォールアイアンイソテルミック・タイトレーション・カロメトリーネイティブ・マススペクトロメトリー共振ラーマン光譜法

さらに関連する動画

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

11.2K
Measurement of Heme Synthesis Levels in Mammalian Cells09:43

Measurement of Heme Synthesis Levels in Mammalian Cells

Published on: July 9, 2015

12.2K

関連する概念動画

Tail-anchoring of Proteins in the ER Membrane01:45

Tail-anchoring of Proteins in the ER Membrane

Tail-anchored, or TA, proteins are estimated to make up to 3-5% of membrane proteins found in the eukaryotic cell. Such proteins have a single transmembrane domain located approximately 30 amino acid residues upstream from the C-terminal end. As a result, the signal recognition particle (SRP) cannot guide a TA protein to the ER membrane for cotranslational insertion. Hence, they are integrated into the ER membrane post-translationally using their C-terminal end as the anchor. TA proteins...
3.2K
Gene Families01:57

Gene Families

Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
9.1K
Aromatic Hydrocarbon Cations: Structural Overview01:18

Aromatic Hydrocarbon Cations: Structural Overview

Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
2.9K
Electron Transport Chain: Complex III and IV01:43

Electron Transport Chain: Complex III and IV

During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
8.0K