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Updated: Sep 9, 2025

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

Published on: September 18, 2013

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Protopineは,急性骨髄性白血病細胞における生存信号のROS媒介阻害を促進することによって,抗白血病効果を発揮する

Ji-Eun Lee1, Byeol-Eun Jeon1, Chan-Seong Kwon1

  • 1Department of Integrated Biological science, Pusan National University, Busan, Republic of Korea.

Anticancer research
|August 28, 2025
PubMed
まとめ

プロトピンは,活性酸素種を増やし,重要な生存経路を阻害することによって,急性骨髄性白血病 (AML) 細胞の分化を効果的に誘導します. この天然化合物は新しいAMLの 差別化治療法として有望です

キーワード:
急性骨髄性白血病抗白血病活動区分する差別化療法プロトピン反応性酸素種

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