心理的ストレスVersus 乳がん患者における結果:乳がん患者における25年間の追跡調査
PubMedで要約を見る
まとめ
この要約は機械生成です。Forsen inventory (FI) は,乳がんの症状のある患者の心理的ストレス (PS) を効果的に測定します. 高いFIスコアは,長期生存の結果が悪いことを予測し,リスクの階層化におけるその有用性を示唆しています.
科学分野
- 腫瘍学
- 心理学
- 医療診断
背景
- 心理的ストレス (PS) は,乳がん (BC) 患者のアウトカムに重要な要因です.
- フォルセン・インベントリ (FI) は,PSの重さを測定するために設計されたツールです.
研究 の 目的
- BCの症状を持つ患者の長期的なアウトカムに対するFIの予測能力を評価する.
- FIスコアと確立された心理的評価ツールとの相関性を評価する.
主な方法
- BC症状のある患者115人がFIスケールを完了しました.
- コックス回帰とカプラン・マイヤー分析を含む生存モデルを使用して,FIスコアと長期的なアウトカムとの関連を分析した.
- FIスコアは,ベックうつ病インベントリー (BDI),モンゴメリー・アスバーグうつ病評価スケール (MADRS),およびステート・トレイト・アンキシーインベントリー (STAI) と相関した.
主要な成果
- FIスコアはBDI (r=0. 678),MADRS (r=0. 820) およびSTAI (r=0. 556) と有意な相関を示した.
- より高いFIスコアは,BC患者における25年無再発生存期 (RFS) の低下 (HR=2. 60,p=0. 05) と,良性乳腺疾患 (BBD) 患者における25年全生存期 (OS) の低下 (HR=7. 79,p=0. 05) を予測した.
- カプラン- メイヤー解析では,低FIスコア (< 14) のBC患者で25年RFSが有意に改善され,低FIスコアのBBD患者で25年OSがより高いことが示されました.
結論
- FIスケールはPSを効果的に把握し,乳腺疾患の患者の長期的な結果を予測します.
- FIを診断評価に組み込むことは,BCの症状を持つ女性のリスクの階層化と管理を強化する可能性があります.
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