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Updated: Sep 9, 2025

Reconstitution of Msp1 Extraction Activity with Fully Purified Components
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MitoTraP: 細胞のプロテオスタシスのためのミトコンドリア保護

Michaela Oborská-Oplová1, Michael A Ruoss1, Vikram G Panse2

  • 1Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.

Trends in biochemical sciences
|August 28, 2025
PubMed
まとめ

細胞は,エネルギーストレスの間にミトコンドリアのタンパク質輸入を管理するために品質管理メカニズムを使用します. このプロセスは,ミトコンドリアの膜間空間に前駆者を閉じ込めることで,細胞溶液と核に潜在的に有毒なタンパク質の蓄積を防止します.

キーワード:
ミトコンドリアの輸入ミトコンドリアの膜間空間ミトコンドリア品質管理ミトコンドリアのリボソームタンパク質 (MRPs)ミトコンドリアのストレスタンパク質毒性ストレス

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