関連する実験動画

Updated: Sep 9, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

838

コロナウイルスのゲノムにおけるG四重複体を合成的に誘導することで,感染性が低下する

YongWoo Lee1, Roy Blum1, Tyler Mrozowich1

  • 1Massachusetts General Hospital.

RNA (New York, N.Y.)
|August 28, 2025
PubMed
まとめ

非正規のRNAG四重複素 (rG4s) は正規の形態とは異なり,ssRNAウイルスに豊富に存在する. これらのrG4をリガンドで標的にすると,ウイルスの複製と感染性が抑制され,潜在的な治療戦略が提供されます.

キーワード:
G クアドルプレックスG クアドルプレックス安定剤OC43 についてRNA構造コロナウイルス

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