高齢者栄養リスク指数: 大腸がん患者における手術後の結果の重要な指標

Fuminori Teraishi^1,2, Masashi Utsumi³, Yusuke Yoshida²

¹Department of Surgery, National Hospital Organization Fukuyama Medical Center, Hiroshima, Japan; teraishi.fuminori.lw@mail.hosp.go.jp.

In vivo (Athens, Greece)

|August 28, 2025

まとめ

老年栄養リスク指数 (GNRI) は,手術による合併症のリスクが高い大腸癌 (大腸癌) の高齢者 (≥85歳) を効果的に特定します. GNRIスコアが低いと栄養状態が悪くなりリスクが高まります

科学分野:

高齢者手術
腫瘍学
栄養評価

背景:

85歳以上の患者における結腸直腸がん (CRC) の手術は,手術前期に重大なリスクを伴う.
栄養状態は,この集団における結果に影響を与える重要な要因です.
高齢者栄養リスク指数 (GNRI) は,栄養状態を評価するための潜在的なツールです.

研究の目的:

CRC手術を受けた年配の患者における手術後の結果の指標としてGNRIを検証する.
この患者グループにおける手術前リスクの階層化におけるGNRIの有用性を評価する.

主な方法:

選択性CRC手術を受けた85歳以上の患者の前向きな研究.
手術前GNRIは血清アルブミンと体重を用いて計算した.
患者はGNRI>98とGNRI>98のグループに分類された.
人口統計,臨床的特徴,高齢者評価 (G8,EQ-5D),手術後の合併症の分析

主要な成果:

24人の患者 (11人のGNRI>98,13人のGNRI>98) を対象とした.
GNRI>98グループは,G8スコアとEQ-5D指数値 (p<0. 01) を有意に改善した.
GNRI ≤98グループは,手術後の合併症率が著しく高かった (p=0. 02).

結論:

手術前GNRIは,合併症のリスクが高い高齢のCRC患者を特定するのに有効です.
GNRI ≤98は栄養状態の低下と老年機能の低下と関連しています.
この脆弱な集団における手術前リスクの階層化に役立つシンプルなツールです

キーワード:

高齢者栄養リスク指数大腸がん一番年上短期的な結果

さらに関連する動画

04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

661

08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

12.9K

関連する概念動画

01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

413

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...

413

01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

282

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...

282

01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

462

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...

462

01:29

Assessment of the Gastrointestinal System II: Health Perception Pattern

162

Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:

162

01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...

関連する実験動画