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Updated: Sep 9, 2025

Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities

Published on: October 2, 2018

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サイクロチドにおける分子内二硫化物ペアリングのマルコヴィア時間スケール

Jayapriya Venkatesan1, Durba Roy1

  • 1Department of Chemistry, Birla Institute of Technology and Science, Pilani, Hyderabad Campus, Hyderabad, India.

Proteins
|August 28, 2025
PubMed
まとめ

この研究は,植物毒素であるサイクロビオラシンO1 (CyO1) の折り畳み動態をモデル化しています. 隠されたマルコフモデルは,固有のペプチド構造の達成に不可欠な,素早い分子内二酸化炭素結合の形成を明らかにする.

キーワード:
マルコフ状態モデルサイクロチドディスルファイド結合分子動力学

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