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Updated: Sep 9, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

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ブロミド触媒によるビアリルボロン酸とSe/Te粉末のラジカルサイクル

Zhouting Zeng1, Yanfeng Ma2, Zi Yang3

  • 1College of Chemistry and Chemical Engineering, University of South China, Hengyang, Hunan 421001, China.

The Journal of organic chemistry
|August 28, 2025
PubMed
まとめ

新しい金属のない方法により,アモニウムブロミドを触媒として使って機能化されたディベンゾセルノフェンとディベンゾテルロフェンの合成が可能である. この効率的で,スケーラブルで,酸化物質のないアプローチは,価値あるヘテロサイクルの化合物への持続可能な経路を提供します.

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Radical Substitution: Allylic Bromination

In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...
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