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Updated: Sep 9, 2025

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
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Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

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抗HBV設計エピジェノーム修正剤を生成するmRNA

Prashika Singh1, Tafadzwa Mlambo2, Kristie Bloom1

  • 1Wits/SAMRC Antiviral Gene Therapy Research Unit, Infectious Diseases and Oncology Research Institute (IDORI), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Methods in molecular biology (Clifton, N.J.)
|August 28, 2025
PubMed
まとめ

新しいエピゲノム編集ツールは,mRNAによって提供される設計エピゲノム修正剤 (DEM) を使用して,慢性B型肝炎ウイルス (HBV) の複製を標的と沈黙させます. このアプローチは HBV 治療の持続的な非変異性戦略として有望です

キーワード:
CpG島DEM についてHBV ウイルスインビトロ転写

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