高度な訓練を受けた競技選手と訓練を受けていない対照群の口腔微生物組成の比較
Annabel Simpson1, Bob T Rosier2, Javier Pons Tamarit2
1Sport and Physical Activity Research Institute, University of the West of Scotland, Blantyre, Scotland.
Scientific reports
|August 28, 2025
まとめ
競争力のあるアスリートは 独特の口腔微生物群のプロファイルを示し,特に舌で,より高いレベルの窒素を減らすバクテリアが 有酸素性の向上に関連しています. これは運動が口腔の微生物群に 影響を及ぼし 全体的な健康に 利益をもたらす可能性があることを示唆しています
科学分野:
- 微生物学
- 運動 生理学
- 口腔 衛生
背景:
- 口腔の微生物群は窒素酸化物 (NO) の生成に重要な役割を果たし,口腔と全身の健康に影響を与えます.
- 運動などのライフスタイル要因が 口内微生物群に どのように影響するかを知ることは 健康研究にとって極めて重要です
研究 の 目的:
- 高度なトレーニングを受けた競技選手と不活発な対照群の口腔微生物組成と窒素酸化物 (NO) 生成マーカーを比較する.
- 運動訓練,口腔微生物の変化,および有酸素運動の間の関係を調査する.
主な方法:
- 10人の競争力のある選手と 10人の非活動的な対照群を募った
- 長読 16S rRNA 配列を用いて唾液,プラズマ,上膜斑,および舌の背中の微生物群を分析した.
- オゾンベースの化学発光を用いた窒素 (NO3-) および窒素 (NO2-) 濃度測定;エアロビックフィットネス評価 (V·O2max).
主要な成果:
- アスリートと対照群の間で,舌の背中の微生物群のベータ多様性が異なっていた (Adonis p=0. 046).
- スポーツ選手は,舌の背中にNO3を減少させるRothia mucilaginosaと未分類のGemella種の相対的な豊富さを示した.
- スポーツ選手の唾液中のNO3- (p=0. 003) とNO2- (p=0. 03) の濃度が著しく高かった.
- R. mucilaginosa,未分類のGemellaとエアロビックフィットネスの間の正の相関が観察されました.
結論:
- 運動は舌の背中の微生物群に選択的に影響を及ぼし,NOの産生に関連する有益な細菌を増やすように見える.
- 結果は,一貫した運動と,より健康的な口腔微生物の組成との間の潜在的な関連を示唆しています.
- 運動と口腔の微生物群と全身の健康を結びつけるメカニズムを明らかにするためにさらなる研究が必要である.
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