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Updated: Sep 9, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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単段階反応と多段階計画との逆合成クロストラック

Junseok Choe1, Hajung Kim1, Yan Ting Chok1

  • 1Department of Computer Science, Korea University, Seoul, South Korea.

Journal of cheminformatics
|August 28, 2025
PubMed
まとめ

多段階のレトロ合成経路の生成は困難です この研究では 単一段階のレトロシンセシスモデルと 計画アルゴリズムを統合し 最良の解明性が 薬剤発見の経路の実現性を保証しないことを発見しました

キーワード:
多段階の逆合成計画リトロシンセシスリトロ合成の実現可能性単段階の逆合成予測

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