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Updated: Sep 9, 2025

Neutron Crystallography Data Collection and Processing for Modelling Hydrogen Atoms in Protein Structures
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デュテリウムガスを用いた化学選択的ベンジルC-Hデュテレーション

Jie-Lun Yan1, Guangrong Meng1, Daniel A Strassfeld1

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Organic letters
|August 29, 2025
PubMed
まとめ

この研究では,デュテリウムガスを用いたベンジルC-Hデュテレーションのための新しいパラジアム触媒法が導入されています. このアプローチは,プロティック溶剤の効率的な同位体ラベル付けを可能にし,薬剤発見とメカニズム研究を進めます.

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