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Updated: Sep 9, 2025

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
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ケラチノサイトにおけるPPARα-オーケストラされたFADS2による脂肪酸代謝の再プログラム 牛皮病における皮膚炎を調節する

Jiangluyi Cai1, Xue Zhou1, Yu Zhuang1

  • 1Department of Dermatology, Shanghai Skin Disease Hospital, Institute of Psoriasis, Tongji University School of Medicine, Shanghai, 200443, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 29, 2025
PubMed
まとめ

脂肪酸脱飽和酵素2 (FADS2) 欠乏症は,ドコサヘキサエノ酸 (DHA) 産生を阻害し,炎症を増加させ,牛皮病を悪化させる. FADS2の活性回復は,この慢性皮膚疾患の 治療戦略の可能性がある.

キーワード:
FADS2 についてPPARα脂肪酸炎症ケラチノサイト牛皮病

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