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Updated: Sep 9, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
06:54

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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TBC1D22Bは,RAB1B不活性化によるER-to-Golgiの輸送を調節し,乳がんにおける腫瘍性プログラムを促進する

Flavia Martino1,2, Mariadomenica Lupi1,2, Alessandra Murabito2

  • 1Department of Oncology, University of Torino Medical School, Candiolo, Torino, 10060, Italy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 29, 2025
PubMed
まとめ

GTPaseを活性化するタンパク質であるTBC1D22Bは,RAB1Bを標的とし,乳がんの成長を促進し,遺伝子発現を変化させ,ER-Golgi輸送を阻害する. これはTBC1D22Bを強調しています.

キーワード:
ERからゴルギへの輸送RAB1B についてRUSH についてラブガップTBC1D22B乳がん

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An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation08:48

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