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Updated: Sep 9, 2025

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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地域特有の脳老化軌道を用いて双極性および単極性うつ病における主要な脳病理の特定:台湾老化および精神疾患コホートからの洞察

Jun-Ding Zhu1,2, I-Jou Chi3,4, Hui-Yun Hsu3,4

  • 1Department of Occupational Therapy, https://ror.org/059ryjv25College of Medical Science and Technology, Chung Shan Medical University, Taichung, Taiwan.

Psychological medicine
|August 29, 2025
PubMed
まとめ

この研究は,双極性障害 (BD) とメジャーうつ病 (MDD) の脳老化の加速を明らかにし,それぞれの状態で影響を受ける一般的なおよびユニークな脳領域を特定しました. これらの発見は 脳の老化経路が 精神疾患のバイオマーカーとして機能することを示唆しています

キーワード:
双極性障害脳の老化経路拡散テンソルイメージング分数アニソトロピー灰色の物質機械学習磁気共鳴画像検査重度のうつ病精神疾患神経イメージング地域特有のモデル標準偏差

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