ベンゾジアゼピンと催眠薬の投与パターンは,前述の薬剤を服用していた高齢者の間で,骨骨折後に発生している

Meng Pan¹, Emilie D Duchesneau², Elyse M Miller¹

¹Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.

Journal of the American Geriatrics Society

|August 29, 2025

まとめ

多くの高齢者は,ベンゾジアゼピン (BZD) またはZ薬を,股関節骨折の入院後に補充しました. これらの高リスク薬の継続的な使用は,介護の移行時に薬のレビューの必要性を強調しています.

科学分野:

老年薬理学
患者の安全
薬剤管理

背景:

ベンゾジアゼピン (BZD) とZ型薬は,高齢者の股関節骨折のリスクを高めます.
転倒や骨折の歴がある患者は,これらの薬剤は避けてください.

研究の目的:

股関節骨折後の BZDとZ薬の補充パターンを評価する
高齢者におけるBZDとZ薬の継続的な使用に関連した要因を調査する.

主な方法:

骨骨折で入院した66歳以上の米国メディケアの受給者による遡及コホート研究.
退院後180日以内に再注入パターン (継続,減量) を分析した.
継続と減期に関連した人口統計的,併発性,および高齢化要因を調べた.

主要な成果:

高齢者の54%以上が,股関節骨折後の180日以内にBZDまたはZ薬の投与を続けた.
継続率は,短期間/中期作用のBZD,長期間作用のBZD,およびZ薬の間で類似していました.
若い年齢と不安は,継続するリスクが高いと関連付けられました.

結論:

高リスクのBZDやZ-ドラッグは,ヒップ骨折の入院後の高齢者の有意な割合で継続されています.
これは介護の移行時に医薬品のレビューと処方停止の必要性を強調しています
この脆弱な集団におけるリスクを軽減するために標的を絞った介入が必要である.

キーワード:

ベンゾジアゼピン描写するヒップ骨折再充填パターン z-ドラッグ

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