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Updated: Sep 9, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Published on: August 11, 2017

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ROS1-TKI治療を受けた非小細胞肺がん患者のROS1融合パートナーと抵抗メカニズムの影響

Fenneke Zwierenga1, Christa Dijkhuizen2, Patrick Korthuis2

  • 1Department of Pulmonary Medicine, University of Groningen, University Medical Center Groningen, The Netherlands.

Molecular oncology
|August 29, 2025
PubMed
まとめ

クリゾチニブやロラチニブのようなTKIで治療されたROS1融合陽性非小細胞肺がん (NSCLC) のアウトカムは様々でした. レジスタンスの変異はロラチニブの有効性に影響し,実際のTKIの有効性が低下した.

キーワード:
非小細胞肺がんROS1 についてレジスタンス

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Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

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