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Updated: Sep 9, 2025

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
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メンデルのランダム化,脂質と冠動脈疾患:研究設計と仮定の間のトレードオフ

Joy Shi1,2,3, Sonja A Swanson2,3,4, Elizabeth W Diemer3,4

  • 1VA Boston Healthcare System, Boston, Massachusetts, USA.

American journal of epidemiology
|August 29, 2025
PubMed
まとめ

メンデルのランダム化 (MR) 試験設計は結果に大きく影響し,2つのサンプルのアプローチは,1つのサンプルの設計とは異なる見積もりを得ている. 研究者は,設計選択が脂質と冠動脈疾患のMRI分析の結果にどのように影響するかを評価すべきである.

キーワード:
メンデルのランダム化冠動脈疾患インストルメンタル変数脂質

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