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Updated: Sep 9, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

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Δ133p53イソフォームは,腫瘍の成長を促進するためにTLR4機能を強化します

Sasini Polwatta Lekamlage1, Alexandra N Boix De Jesus1,2, Adriana Machado Saraiva1,3

  • 1Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, 9016, New Zealand.

Carcinogenesis
|August 29, 2025
PubMed
まとめ

Δ133p53のような腫瘍タンパク質53 (TP53) アイソフォームは癌の成長を促します. Toll-like受容体4 (TLR4) などの細胞表面タンパク質を標的にすることで,Δ133p53による腫瘍の進行と転移を抑制する新しい戦略が提供されます.

キーワード:
API5 について癌についてTLR4 について細胞表面Δ133p53

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